User talk:Rah175/Benchmark II: Model Description

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Student Comments

The descriptions for the equations are a bit vague and difficult to understand, if elaborated more upon, I think the model description would be good. Probably should elaborate more on the relevance of neuron spiking and narcolepsy earlier. Also I think in equation 2, the word is affect not effect. I would also put the additional descriptions of the parameters below the parameter table, not above. I think the structure of the description is good. --Janet Wang (talk) 11:09, 17 April 2017 (EDT)

The equations and parameters are clearly displayed in the chart, but it would be nice to have a little more context to the equations. I understand how the order influences the equation but I'd be more interested to know the context behind that decision. I like the description of the parameters in that section, perhaps add a small description in parenthesis next to each variable as it is hard to follow what they mean since that is the first time they are introduced in the text.. --Chiraag Lathia (talk) 11:59, 18 April 2017 (EDT)

Instructor Comments

  • Benchmark submitted on time?
    • Yes
  • Rubric submitted on time?
    • Yes
  • State variables, parameters and inputs to the model clearly distinguished?
    • Yes; values for parameters do not all appear to correct; please check this.
  • Term-by-term description of model components?
    • The description of the equations is not really right. You do not seem to really understand how the u recovery variable and the v variable work, or what they do after re-set occurs. This will need to be corrected in your final description of the model.
  • Have you described model assumptions?
    • When you say “ a set of 2 two-dimensional differential equations can be used in order to model the Hodgkin-Huxley model presented by Eugene Izhikevich”, you show a fundamental misunderstanding of what the Izhikevich model is trying to do, and of the Hodgkin Huxley model. The Hodgkin Huxley model captured a very restricted number of ionic conductances, and was designed primarily to capture axonal transmission in the squid giant axon. As described in detail in Chapter 7 of the book, which you need to read carefully, it was subsequently extended by the description of a large number of additional ionic conductances. Izhikevich has done a careful dynamical analysis of these more complex models, and has been able to capture their properties with his much more simple model. So, his model is not a Hodgkin Huxley model, but a greatly simplified model that captures the dynamics of neural models that are more complex than the Hodgkin Huxley model. You say “We can assume that the alpha/beta waves created from the neuronal network will represent common alpha/beta waves in people with narcolepsy.” What articles from the technical literature can you cite to support this assumption? If you have no citations, it is unlikely that the reader of your paper will accept that this assumption is correct or true.
  • Description of equation simulation?
    • This could be both more detailed and clearer. You have also entirely omitted a description of how the synaptic matrix will be implemented, and this is a critical part of the entire model.

On the whole, this is a poor to fair first draft of a model description section. Please follow the suggestions above to improve it. You will also need to add additional details to describe the extension to the model.

--Hillel Chiel (talk) 12:26, 9 April 2017 (EDT)